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    產品資料

    Cynomolgus OX-40L / TNFSF4 Protein|技術資料|現貨

    產品名稱: Cynomolgus OX-40L / TNFSF4 Protein|技術資料|現貨
    產品型號: C86-900-88
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    Cynomolgus OX-40L / TNFSF4 Protein|技術資料|現貨由上海創賽科學儀器有限公司品質提供。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    Cynomolgus OX-40L / TNFSF4 Protein|技術資料|現貨  的詳細介紹

    OX-40L / TNFSF4蛋白產品信息

    別名: TNFSF4
    表達方式: 
    A DNA sequence encoding the cynomolgus TNFSF4 (F7FL80) (Gln51-Leu183) was expressed with the Fc region of mouse IgG1 at the N-terminus.
    種屬: Cynomolgus
    表達宿主: Human Cells

    OX-40L / TNFSF4 Protein QC Testing

    純度: > 85 % as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Asp
    分子量: 
    The recombinant cynomolgus TNFSF4 is a disulfide-linked homodimer. The reduced monomer comprises 369 amino acids and has a calculated molecular mass of 42 KDa.The apparent molecular mass of it is approximately 48 KDa respectively in SDS-PAGE.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    OX-40L / TNFSF4 Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    OX-40L / TNFSF4蛋白背景綜述

    OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.

    參考文獻

    Lei W. et al., 2012, Ann Acad Med Singapore. 41 (5): 200-4.
    Lee YH. et al., 2012, Hum Immunol. 73 (10): 1050-4.
    Weiguang Y. et al., 2012, PLoS One. 7 (8): e41277.

    規格:20ug

    關 鍵 詞:Cynomolgus OX-40L / TNFSF4 Protein,技術資料,現貨,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的Cynomolgus OX-40L / TNFSF4 Protein|技術資料|現貨性能**,其優良的品質滿足您不同實驗的多種需求。

    本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com

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