GALNT2 / GalNAc-T2蛋白產品信息
別名: GALNT2 表達方式: A DNA sequence encoding the human GALNT2 (NP_004472.1) (Lys52-Gln571) was expressed with an N-terminal polyhistidine tag. 種屬: Human 表達宿主: Human Cells GALNT2 / GalNAc-T2 Protein QC Testing
純度: (94.8+3.9) % as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: His 分子量: The recombinant human GALNT2 comprises 540 amino acids and has a predicted molecular mass of 61.6 kDa. The apparent molecular mass of the protein is approximately 57-65 and 46 kDa in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile 25 mM Tris, 150 mM NaCl, 0.05% Brij-35, pH 7.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. GALNT2 / GalNAc-T2 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. GALNT2 / GalNAc-T2蛋白背景綜述
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. GALNT2 may play a role in lipid metabolism. It catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT2 has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. 參考文獻
Bennett EP. et al., 1998, Glycobiology. 8 (6): 547-55. White T. et al., 1995, J Biol Chem. 270 (41): 24156-65. Bennett EP. et al., 1996, J Biol Chem. 271 (29): 17006-12. Holleboom AG. et al., 2011, Cell Metab. 14 (6): 811-8. 關 鍵 詞:GALNT2 / GalNAc-T2 Protein,GALNT2 / GalNAc-T2蛋白質,使用說明,價格,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
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