RAB27B Protein|RAB27B蛋白質|使用說明|價格

RAB27B蛋白產品信息

別名: RAB27B
表達方式: 
A DNA sequence encoding the human RAB27B (NP_004154.2) (Thr2-Lys215) was expressed with an N-terminal polyhistidine tag.
種屬: Human
表達宿主: Human Cells

RAB27B Protein QC Testing

純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: His
分子量: 
The recombinant human RAB27B comprises 234 amino acids and has a predicted molecular mass of 26.6 kDa. The apparent molecular mass of the protein is approximately 29 kDa in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

RAB27B Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

RAB27B蛋白背景綜述

RAB27B is a a regulator of vesicle exocytosis. It delivers proinvasive signals for increased invasiveness, tumor size, and metastasis of various estrogen receptor (ER)-positive breast cancer cell lines, both in vitro and in vivo. In human breast cancer specimens, RAB27B associates with a low degree of differentiation and the presence of lymph node metastasis in ER-positive breast cancer. RAB27B belongs to the Rab protein family which are composed of prenylated, membrane-bound proteins involved in vesicular fusion and trafficking.

參考文獻

Hendrix A. et al., 2010, Oncotarget. 1 (4): 304-8.
Tanaka C. et al., 2012, Biochem Biophys Res Commun. 419 (2): 368-73.
Zhang JX. et al., 2012, J Transl Med. 10: 242.

規格：50ug

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