BPIFB1 / LPLUNC1 Protein|BPIFB1 / LPLUNC1 蛋白質|技術資料|價格

BPIFB1 / LPLUNC1蛋白產品信息

別名: BPIFB1, C20orf114, LPLUNC1
表達方式: 
A DNA sequence encoding the human BPIFB1 (AAH08429.1) (Met1-Gln484) was expressed with a polyhistidine tag at the C-terminus.
種屬: Human
表達宿主: Human Cells

BPIFB1 / LPLUNC1 Protein QC Testing

純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per μg of the protein as determined by the LAL method
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Thr 22
分子量: 
The recombinant human BPIFB1 consists of  474 amino acids and predicts a molecular mass of  51.7 KDa. It migrates as an approximately 53 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

BPIFB1 / LPLUNC1 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

BPIFB1 / LPLUNC1蛋白背景綜述

BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.

參考文獻

Bingle CD. et al., 2011, Biochem Soc Trans. 39 (4): 977-83.
Shin OS. et al., 2011, J Infect Dis. 204 (9): 1349-57.
Bingle L. et al., 2012, Histochem Cell Biol. 138 (5): 749-58.

規格：10ug

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