EWI-F / PTGFRN蛋白產品信息
別名: PTGFRN 表達方式: A DNA sequence encoding the cynomolgus PTGFRN (H9ERH4) (Met1-Lys830) was expressed with a polyhistidine tag at the C-terminus. 種屬: Cynomolgus 表達宿主: Human Cells EWI-F / PTGFRN Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Val 26 分子量: The recombinant cynomolgus PTGFRN comprises 816 amino acids and has a calculated molecular mass of 91.5 KDa. The apparent molecular mass of it is approximately 96-106 KDa in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. EWI-F / PTGFRN Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. EWI-F / PTGFRN蛋白背景綜述
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT (n=55). EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours. 參考文獻
Stipp C S. et al., 2001, J Biol Chem. 276 (7): 4853-62. Charrin S. et al., 2001, J Biol Chem. 276 (17): 14329-37. Orlicky DJ. et al., 1996, Hum Genet. 97 (5): 655-8. 規格:20ug 關 鍵 詞:Cynomolgus EWI-F / PTGFRN Protein,技術資料,廠家現貨,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
CANSPEC品質提供的Cynomolgus EWI-F / PTGFRN Protein|技術資料|廠家現貨性能**,其優良的品質滿足您不同實驗的多種需求。
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