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    產品資料

    ITGA5 & ITGB6 Heterodimer Protein|技術資料|價格

    產品名稱: ITGA5 & ITGB6 Heterodimer Protein|技術資料|價格
    產品型號: C86-CT0-39
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    ITGA5 & ITGB6 Heterodimer Protein|技術資料|價格由上海創賽科學儀器有限公司品質提供,可查詢ITGA5 & ITGB6 Heterodimer Protein價格。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    ITGA5 & ITGB6 Heterodimer Protein|技術資料|價格  的詳細介紹

    ITGA5 & ITGB6 Heterodimer蛋白產品信息

    別名: ITGA5 & ITGB6
    表達方式: 
    A DNA sequence encoding the extracellular domain (Met1-Val992) of human ITGAV (P06756-1) was fused with a flag tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asn707) of human ITGB6 (P22646) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB6 heterodimer was purified.
    種屬: Human
    表達宿主: Human Cells

    ITGA5 & ITGB6 Heterodimer Protein QC Testing

    純度: > 95 % as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Phe 31 & Gly 22
    分子量: 
    The recombinant heterodimer of human ITGAV&ITGB6 comprises 1731 (1003+728) amino acids and has a calculated molecular mass of 190.4 (111.1+79.3) KDa. As a result of glycosylation, the apparent molecular mass of human ITGAV&ITGB6 heterodimer is approximately 119 and 89-105 KDa in SDS-PAGE under reducing conditions.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    ITGA5 & ITGB6 Heterodimer Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    ITGA5 & ITGB6 Heterodimer蛋白背景綜述

    Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.

    參考文獻
    Sosnoski DM. et al., 1988, J Clin Invest. 81 (6): 1993-8.
    Tani T T. et al., 2001, J Biol Chem. 276 (39): 36535-42.
    Krissansen GW. et al., 1992, Immunogenetics. 35 (1): 58-61.

    規格:10ug

    關 鍵 詞:ITGA5 & ITGB6 Heterodimer Protein,技術資料,價格,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的ITGA5 & ITGB6 Heterodimer Protein|技術資料|價格性能**,其優良的品質滿足您不同實驗的多種需求。

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