TDGF1 / CRGF蛋白產品信息
別名: TDGF1 表達方式: A DNA sequence encoding the rat TDGF1 (XP_001056317.2) (Met1-Cys143) was expressed with a polyhistidine tag at the C-terminus. 種屬: Rat 表達宿主: Human Cells TDGF1 / CRGF Protein QC Testing
純度: (32.6+48.9) % as determined by SDS-PAGE SDS-PAGE 內**: < 1.0 EU per μg of the protein as determined by the LAL method 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Phe 17 分子量: The recombinant rat TDGF1 comprises 138 amino acids and predicts a molecular mass of 15.5 kDa. The apparent molecular mass of the recombinant protein is approximately 22 and 19 kDa in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. TDGF1 / CRGF Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. TDGF1 / CRGF蛋白背景綜述
Teratocarcinoma-derived growth factor 1, also known as Epidermal growth factor-like cripto protein CR1, CRGF, and TDGF1, is a cell membrane which contains one EGF-like domain. In humans, TDGF1 is highly expressed in germ cell tumors and in colon and mammary carcinomas. TDGF1 is a member of the epidermal growth factor-cripto FRL1 cryptic protein family and is involved in the activation of several different signaling pathways during embryonic development and cellular transformation. TDGF1 regulates the activation of several signaling pathways and controls cellular transformation in embryonic status. Patients with high TDGF1 expression were statistically susceptible to a recurrence of the disease, and showed poorer disease-free survival than those with low expression. TDGF1 is a predictive marker for metachronous metastasis in colorectal cancer (CRC) patients. It is preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. TDGF1 plays a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. 參考文獻
Liguori G. et al., 1996, Mamm Genome. 7 (5): 344-8. De la Cruz. et al., 2002, J M Hum Genet. 110 (5): 422-8. Liguori G. et al., 1997, Mamm Genome. 8 (7): 502-5. Miyoshi N. et al., 2010, Int J Oncol. 36 (3): 563-8. 規格:10ug 關 鍵 詞:Rat TDGF1 / CRGF Protein,鼠TDGF1 / CRGF蛋白質,技術資料,價格,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家
CANSPEC品質提供的Rat TDGF1 / CRGF Protein|鼠TDGF1 / CRGF蛋白質|技術資料|價格性能**,其優良的品質滿足您不同實驗的多種需求。
本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com
國內免費服務專線:400 608 7598(據說天才可以在15秒內記住我們的免費電話哦^_^)
服務升級,全新企業QQ為您服務,企業QQ號:4006087598
創賽官網升級為創賽優選商城,請移步www.canspec.cn注冊登錄,新用戶注冊送1000元現金券
滬公網安備 31011402005168號