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    產品資料

    Rat ALCAM / CD166 Protein|鼠ALCAM / CD166蛋白質|參數|現貨|使用說明

    產品名稱: Rat ALCAM / CD166 Protein|鼠ALCAM / CD166蛋白質|參數|現貨|使用說明
    產品型號: C86-802-21
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    Rat ALCAM / CD166 Protein|鼠ALCAM / CD166蛋白質|參數|現貨|使用說明由上海創賽科學儀器有限公司品質提供,可查詢鼠ALCAM / CD166蛋白質價格。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    Rat ALCAM / CD166 Protein|鼠ALCAM / CD166蛋白質|參數|現貨|使用說明  的詳細介紹


    別名: ALCAM
    表達方式: 
    A DNA sequence encoding the rat ALCAM (O35112) (Met1-Lys527) was expressed with the Fc region of human IgG1 at the C-terminus.
    種屬: Rat
    表達宿主: Human Cells
    ALCAM / CD166 Protein QC Testing

    純度: > 95 % as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Trp 28
    分子量: 
    The recombinant rat ALCAM/Fc is a disulfide-linked homodimer. The reduced monomer comprises 741 amino acids and has a predicted molecular mass of 83.1 kDa. The apparent molecular mass of the protein is approximately 94 kDa in SDS-PAGE under reducing conditions due to glycosylation.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    ALCAM / CD166 Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    ALCAM / CD166蛋白背景綜述

    ALCAM (activated leukocyte cell adhesion molecule) is a type I membrane glycoprotein and a member of the immunoglobulin superfamily. It is also known as CD166, MEMD, SC-1/DM-GRASP in the chicken, and KG-CAM in the rat. ALCAM / CD166 has five extracellular immunoglobulin-like domains which facilitates heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. While expressed in a wide variety of tissues and cells, ALCAM is restricted to subsets of cells usually involved in dynamic growth and / or migration processes. ALCAM is highly associated not only with embryonic hematopoiesis but also vasculoangiogenesis. ALCAM can bind itself homotypically and is also capable of binding CD6, NgCAM, and other unidentified brain proteins, and thus is Involved in neurite extension by neurons via heterophilic and homophilic manners. ALCAM / CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- cells and B-cells to activated leukocytes. Further, ALCAM has also been observed to be upregulated on highly metastasizing melanoma cell lines, suggesting a role in tumor migration.

    參考文獻

    Bowen MA. et al., 1995, J Exp Med. 181:2213-20.
    Aruffo A. et al., 1997, Immunol Today. 18: 498-504.
    Degen W. G. et al., 1998, Am J Pathol. 152: 805-13.
    Van K. L. et al., 2001, J Biol Chem. 276: 25783-9.
    Hirata H. et al., 2006, Cells Tissues Organs. 184 (3-4):172-80.
    Jezierska A. et al., 2006, Med Sci Monit.12 (7): BR245-256.

    規格;50ug

    關 鍵 詞:Rat ALCAM / CD166 Protein,鼠ALCAM / CD166蛋白質,參數,現貨,使用說明,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的Rat ALCAM / CD166 Protein|鼠ALCAM / CD166蛋白質|參數|現貨|使用說明性能**,其優良的品質滿足您不同實驗的多種需求。

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