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    產品資料

    Rat CD8A / Lyt2 Protein|鼠CD8A / Lyt2蛋白質|廠家現貨|技術資料

    產品名稱: Rat CD8A / Lyt2 Protein|鼠CD8A / Lyt2蛋白質|廠家現貨|技術資料
    產品型號: C86-802-85
    產品展商: 博飛美科
    產品文檔: 無相關文檔

    簡單介紹

    Rat CD8A / Lyt2 Protein|鼠CD8A / Lyt2蛋白質|廠家現貨|技術資料由上海創賽科學儀器有限公司品質提供,可查詢鼠CD8A / Lyt2蛋白質價格。上海創賽科學儀器有限公司是專業**試劑生產及供應商,其優良的品質滿足您不同實驗的多種需求,歡迎撥打4006087598洽談選購,更多產品詳情請登錄www.getprovidencehotels.com


    Rat CD8A / Lyt2 Protein|鼠CD8A / Lyt2蛋白質|廠家現貨|技術資料  的詳細介紹

    CD8A / Lyt2蛋白產品信息

    別名: CD8A
    表達方式: 
    A DNA sequence encoding the rat CD8A (P07725) (Met1-Tyr189) was expressed with the Fc region of human IgG1 at the C-terminus.
    種屬: Rat
    表達宿主: Human Cells

    CD8A / Lyt2 Protein QC Testing

    純度: > 90 % as determined by SDS-PAGE SDS-PAGE
    內**: < 1.0 EU per μg of the protein as determined by the LAL method
    穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
    預測N端: Gln 27
    分子量: 
    The recombinant rat CD8A/Fc is a disulfide-linked homodimer. The reduced monomer comprises 404 amino acids and has a predicted molecular mass of 45 kDa. The apparent molecular mass of the protein is approximately 46 kDa in SDS-PAGE under reducing conditions due to glycosylation.
    緩沖液: Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    Please contact us for any concerns or special requirements.

    CD8A / Lyt2 Protein Usage Guide

    儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
    Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

    CD8A / Lyt2蛋白背景綜述

    T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

    參考文獻

    Devine L. et al., 2000, J Immunol. 164 (2): 833-8.
    Arcaro A. et al., 2000, J Immunol. 165 (4): 2068-76.
    Saha K. et al., 2001, Nat Med. 7 (1): 65-72.
    Romero P. et al., 2005, Eur J Immunol. 35 (11): 3092-4.

    規格:2ug

    關 鍵 詞:Rat CD8A / Lyt2 Protein,鼠CD8A / Lyt2蛋白質,廠家現貨,技術資料,實驗室耗材,生化試劑,上海創賽,博飛美科,實驗儀器,廠家

    CANSPEC品質提供的Rat CD8A / Lyt2 Protein|鼠CD8A / Lyt2蛋白質|廠家現貨|技術資料性能**,其優良的品質滿足您不同實驗的多種需求。

    本產品由上海創賽品質提供,歡迎咨詢國內免費服務專線:400-608-7598,更多產品信息請登錄www.getprovidencehotels.com 或 www.4006087598.com

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