Statherin / STATH Protein|Statherin / STATH蛋白質|使用說明|價格

Statherin / STATH Protein Product Information

Synonym : STATH
Protein Construction: A DNA sequence encoding the human STATH (P02808-1) (Met1-Phe62) was fused with Fc region of mouse IgG at the C-terminus.
Source: Human
Expression Host: Human Cell

Statherin / STATH Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Asp 20
Molecular Mass: The recombinant human STATH/mFc is a disulfide-linked homodimer. The reduced monomer comprises 277 amino acids and has a predicted molecular mass of 31.6 kDa. The apparent molecular mass of the protein is approximately 36 in SDS-PAGE under reducing conditions.
Formulation: Lyophilized from sterile PBS, pH 7.4.
                1.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
                2.Please contact us for any concerns or special requirements.

Statherin / STATH Protein Usage Guide

Storage:  Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:  A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Statherin / STATH Protein Description

Statherin, also known as STATH, belongs to the histatin/statherin family. Statherin may play an important role in the maintenance of oral health.It prevents calcium phospate precipitation in saliva, so maintaining a high calcium level in saliva and preventing teeth from dissolving. Statherin also inhibits spontaneous precipitation of calcium phosphate salts. Thus, statherin and PRPs may prevent build-up of harmful deposits in the salivary glands and on the tooth surfaces.Statherin is a highly stable salivary protein of low molecular mass (5,380). Sabatini et al. synthesized mixed oligonucleotides based on the known amino acid sequence of statherin and used these to screen a cDNA library constructed from human parotid gland mRNA.

References

Sabatini LM. et al., 1998, Am J Hum Genet. 41 (6): 1048-60.
Schlesinger DH. et al., 1997, J Biol Chem. 252 (5): 1689-95.
Raj PA. et al., 1992, J Biol Chem. 267 (9): 5968-76.
Douglas WH. et al., 1991, Biochem Biophys Res Commun. 180 (1): 91-7.

規格：100ug

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